The first trans-Andean lodge-to-lodge trek to Machu Picchu follows the Salkantay Route; an ancient trail located in the Cordillera Vilcabamba, the spectacular Andean mountain range home to Machu Picchu.

The starting point is the Salkantay Lodge, which is located in the high Andean valley of Soraypampa at 3,850m above sea level. In addition to high-quality cuisine, the lodge offers weary trekkers an outdoor hot tub, cosy reading rooms, a bar and lounge and twelve well-appointed double rooms with ensuite bathrooms.

After the first two nights spent here, trekkers continue their journey, spending one night at the three remaining lodges; Wayra Lodge at Huayraccmachay, Colpa Lodge at Collpapampa and Lucma Lodge at Lucmabamba. Although these lodges are smaller in size, each offers the same amenities as the base lodge.

The final night is spent at a hotel in Aguas Calientes - Machu Picchu's base town, and after breakfast the following day the group will explore the ruins with a guide. As of 2016, Mountain Lodges of Peru can offer the same comfortable trekking experience, following the Lares trail, as well as the Salkantay.